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2026

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Surface Cosine-Wave–Enabled Single-Particle-Level Dual-Parameter Chirality Detection

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The Luping Du group at Shenzhen University has developed a dual-parameter chiral sensing platform based on surface cosine waves (SCWs), capable of simultaneously capturing both amplitude and phase asymmetries at the single-particle level. SCWs can generate a polarization‑balanced interference field composed of equal‑amplitude left‑handed and right‑handed circularly polarized components, with an intrinsic π‑phase difference. Upon interaction with a chiral scatterer, this symmetry is broken, encoding the structure’s chiral information into two distinct metrics: circular scattering dichroism (CSD) and circular scattering retardance (CSR). Together, these parameters enable a comprehensive electromagnetic characterization of chiral properties at the single-particle scale. This approach provides a robust and universally applicable framework for high‑sensitivity single‑particle chiral sensing, holding promise for advancing next‑generation chiral optical measurement technologies and devices.

The research findings were published in Science Advances on August 5, 2026, under the title “Dual-parameter chiral detection at the single-particle level enabled by surface cosine waves.”

Figure 1: Generation of Surface Cosine Waves (SCWs) and Interference Symmetry

Figure 2: Detection of chiral-induced amplitude and phase asymmetry enabled by surface cosine waves (SCWs)

Figure 3: Dependence of CSD and CSR on the geometric parameters of the gamma-cross structure

Figure 4: Experimental implementation of single-particle chiral sensing based on surface cosine waves (SCWs)

Figure 5: Chiral sensing of single gold helical particles via chemical synthesis based on surface cosine waves (SCWs)

Source: Optics World